The use and abuse of drugs: Acquired immunodeficiency syndrome (AIDS): a late twentieth century -- Infectious disease -- Targeting HIV, the causative virus -- Antiretrovirals: the big picture -- Inhibitors of the HIV reverse transcriptase enzyme -- Inhibitors of the HIV protease enzyme -- Inhibitors of the HIV integrase enzyme -- Inhibitors of viral entry -- HIV/AIDS treatment guidelines -- Ongoing HIV/AIDS drug discovery efforts.